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Prescribing Safety Check
Day 2 Post-NSTEMI
Mr Alan Park · 58 · Male · Cardiology Ward · Post-PCI
6 errors hidden
Y2 / Finals
Cardiology
Post-MI prescribing
🔍
How to use this exercise
This prescription chart looks like a real drug chart — no errors are marked. Work through it systematically as you would in clinical practice. Click any cell, field or row to check it.
If you find an error, the cell will reveal what's wrong and what the correct prescription should be. Correct cells will briefly confirm they're fine. There are 6 errors hidden somewhere on this chart — find them all.
Errors found
0 / 6
Northbridge General Hospital NHS Trust
Acute Inpatient Medication Administration Record
Chart No: 2
Ward: Cardiology
Ward: Cardiology
Surname
PARK
✓ Correct
First name
Alan
✓ Correct
Date of birth
14 / 03 / 1964
❌ Error 1 — Wrong date of birth
DOB recorded as 1964, making the patient 62 years old. Mr Park is 58, born 14/03/1966.
✓ Correct: 14 / 03 / 1966. Always verify patient identity using two identifiers (name + DOB) before prescribing or administering any medication. DOB errors risk wrong-patient administration.
Hospital No.
NB-447821
✓ Correct
Weight
88 kg
✓ Correct
Consultant
Dr S. Mehta
✓ Correct
Date of admission
20 / 02 / 2026
✓ Correct
Diagnosis
NSTEMI — post-PCI day 2 (DES to LAD)
✓ Correct
⚠ Allergies & adverse reactions
NKDA — No Known Drug Allergies
Signed: Dr T. Rees · 20/02/26
✓ Allergy section completed and signed — correct
Clinical context —
Day 2 post-NSTEMI. PCI + drug-eluting stent (DES) to LAD performed yesterday. Contrast angiogram 24h ago. eGFR today 68. K⁺ 4.2 mmol/L. BP 118/74. HR 62 sinus rhythm. Currently eating and drinking.
Regular medications — post-PCI day 2
| # | Drug (approved name) | Dose | Route | Frequency | Start date | Indication | Prescriber / notes |
|---|---|---|---|---|---|---|---|
| 1 |
— no entry —
❌ Error 2 — Omission: aspirin not prescribed
After PCI with a drug-eluting stent (DES), dual antiplatelet therapy (DAPT) is mandatory for a minimum of 12 months. DAPT = aspirin + a P2Y12 inhibitor (ticagrelor). Ticagrelor is prescribed on row 2, but aspirin has been completely omitted. Without aspirin, stent thrombosis risk increases significantly.
✓ Correct: Aspirin 75 mg OD PO — continue indefinitely post-PCI. Ticagrelor 90 mg BD continues alongside for 12 months (DAPT). Do not stop either without cardiology advice.
⚠ Stent thrombosis risk — potentially fatal
|
||||||
| 2 | TICAGRELOR ✓ Correct drug
|
90 mg ✓ Correct dose
|
PO ✓ Correct route
|
BD ✓ Correct frequency
|
21/02/26 ✓ Correct
|
DAPT — post-DES ✓ Correct
|
Dr T. Rees · GMC 7823441 ✓ Correct
|
| 3 | ATORVASTATIN ✓ Correct drug
|
80 mg ✓ Correct dose
|
PO ✓ Correct route
|
OD nocte ✓ Correct frequency
|
21/02/26 ✓ Correct
|
High-intensity statin ✓ Correct
|
Dr T. Rees · GMC 7823441 Take at night ✓ Correct
|
| 4 | RAMIPRIL ✓ Correct drug (ACEi indicated post-MI)
|
10 mg
❌ Error 3 — Wrong dose: ramipril started too high
Ramipril 10 mg is a fully-titrated maintenance dose. Starting at 10 mg post-MI causes dangerous first-dose hypotension, which can be severe in patients with borderline blood pressure post-infarct. This patient's BP is 118/74 — already relatively low.
✓ Correct: Start ramipril at 2.5 mg OD (or 1.25 mg if systolic <120). Titrate slowly: 2.5 → 5 → 10 mg over weeks, checking BP and renal function at each step (NICE NG185).
|
PO ✓ Correct route
|
OD ✓ Correct frequency
|
21/02/26 ✓ Correct
|
Post-MI — ACEi ✓ Correct indication
|
Dr T. Rees · GMC 7823441 ✓ Correct
|
| 5 | BISOPROLOL ✓ Correct drug (beta-blocker indicated post-MI)
|
10 mg
❌ Error 4 — Wrong dose: bisoprolol starting dose too high
Bisoprolol 10 mg is a high maintenance dose. Starting beta-blockade at 10 mg post-MI causes profound bradycardia and hypotension. At HR 62 and BP 118/74, this patient is at significant risk of haemodynamic compromise from a high starting dose.
✓ Correct: Start bisoprolol at 1.25 mg OD. Titrate slowly every 2 weeks: 1.25 → 2.5 → 3.75 → 5 → 7.5 → 10 mg, tolerating HR ≥50 and SBP ≥90 at each step (ESC post-MI guideline).
|
PO ✓ Correct route
|
OD ✓ Correct frequency
|
21/02/26 ✓ Correct
|
Post-MI — beta-blocker ✓ Correct indication
|
Dr T. Rees · GMC 7823441 ✓ Correct
|
| 6 | FUROSEMIDE ✓ Correct drug (loop diuretic for HF)
|
500 mg
❌ Error 5 — Wrong dose: furosemide 500mg (10× standard dose)
Furosemide 500 mg is ten times the standard starting dose. This dose is occasionally used in resistant oedema in renal failure patients under specialist supervision — it is completely inappropriate here. This would cause severe electrolyte derangement (hypokalaemia, hyponatraemia), acute kidney injury, and dangerous hypotension.
✓ Correct: Furosemide 40 mg OD PO is the standard starting dose for mild heart failure or mild fluid overload post-MI. Titrate according to daily weights and renal function. Monitor U&E closely.
⚠ 10× overdose — severe electrolyte disturbance / AKI risk
|
PO ✓ Correct route
|
OD (morning) ✓ Correct frequency
|
21/02/26 ✓ Correct
|
Fluid overload — post-MI ✓ Correct indication
|
Dr T. Rees · GMC 7823441 ✓ Correct
|
| 7 |
METFORMIN
❌ Error 6 — Metformin not withheld post-contrast angiogram
Mr Park had a contrast angiogram 24 hours ago. Metformin must be withheld for 48 hours after iodinated contrast due to the risk of contrast-induced nephropathy (CIN), which causes acute renal impairment, metformin accumulation, and metformin-associated lactic acidosis (MALA).
✓ Correct: Withhold metformin for 48 hours post-contrast (until 22/02/26). Check U&E and eGFR at 48h — if eGFR stable ≥45, restart metformin. If eGFR has fallen, seek senior review before restarting (MHRA guidance).
⚠ Lactic acidosis risk post-contrast
|
1g ✓ Dose correct (if withheld appropriately)
|
PO ✓ Correct route
|
BD ✓ Correct frequency
|
21/02/26 ✓ Note: this drug should be withheld post-contrast — check the drug name cell
|
Type 2 diabetes ✓ Correct indication
|
Dr T. Rees · GMC 7823441 ✓ Correct
|
| 8 | PARACETAMOL ✓ Correct drug
|
1g ✓ Correct dose
|
PO ✓ Correct route
|
QDS PRN ✓ Correct frequency
|
21/02/26 ✓ Correct
|
Analgesia PRN ✓ Correct
|
Dr T. Rees · GMC 7823441 ✓ Correct
|
| 9 | OXYGEN ✓ Correct — oxygen prescribed as a drug with target saturation
|
Target SpO₂ 94–98% ✓ Correct target for this patient (no COPD)
|
Inhaled ✓ Correct route
|
PRN — titrate ✓ Correct — only if SpO₂ below target
|
21/02/26 ✓ Correct
|
Hypoxaemia ✓ Correct indication
|
Dr T. Rees · GMC 7823441 Wean if SpO₂ >94% ✓ Correct
|
Prescribing doctor
Dr T. Rees FY2
✓ Signed
GMC number
7823441
✓ GMC number present
Bleep
4421
✓ Contact details present
Date / time
21/02/2026 · 08:30
✓ Date and time documented
Click any cell on the prescription chart above to check it · 6 errors are hidden somewhere
Answer guide
6 errors
E1
Wrong date of birth — 1964 instead of 1966
Admin error
▼
As prescribed
DOB: 14 / 03 / 1964 (age 62)
Correct
DOB: 14 / 03 / 1966 (age 58) — Mr Alan Park
Prescribing to the wrong patient or using the wrong identifying information is a medication safety never event. Two patient identifiers — full name and date of birth — must be verified against the patient's wristband before prescribing or administering any medication. A 2-year DOB error on a drug chart could result in wrong-patient drug administration if a second patient with a similar name is on the same ward.
E2
Aspirin omitted — DAPT incomplete after drug-eluting stent
Omission
▼
As prescribed
Ticagrelor 90 mg BD only — aspirin not prescribed
Correct
Aspirin 75 mg OD + ticagrelor 90 mg BD (DAPT) — both required for minimum 12 months post-DES
After percutaneous coronary intervention (PCI) with a drug-eluting stent (DES), dual antiplatelet therapy (DAPT) is the gold standard to prevent in-stent thrombosis. DAPT = aspirin (COX-1 inhibitor) + a P2Y12 inhibitor (ticagrelor or clopidogrel). Both mechanisms are needed: aspirin alone is insufficient to prevent stent thrombosis, and ticagrelor alone leaves thromboxane A₂-mediated platelet activation unblocked. ESC and NICE guidelines: continue DAPT for 12 months post-DES unless major bleeding occurs. Stopping aspirin significantly increases stent thrombosis risk.
⚠ Stent thrombosis risk — potentially fatal
E3
Ramipril 10 mg — too high a starting dose post-MI
Wrong dose
▼
As prescribed
Ramipril 10 mg OD — first post-MI dose
Correct
Ramipril 2.5 mg OD starting dose, titrate over weeks to 10 mg OD target (NICE NG185)
ACE inhibitors are commenced at the lowest dose after MI because the renin-angiotensin system is upregulated in the peri-infarct period. Starting at 10 mg causes first-dose hypotension, which reduces coronary perfusion in an already ischaemic myocardium. BP of 118/74 already indicates the patient is at risk of hypotension. NICE NG185 and SIGN 148 both specify starting at 2.5 mg and titrating. Blood pressure and renal function must be checked before each dose increase.
E4
Bisoprolol 10 mg — maximum dose started immediately post-MI
Wrong dose
▼
As prescribed
Bisoprolol 10 mg OD — first post-MI dose
Correct
Bisoprolol 1.25 mg OD starting dose, titrate every 2 weeks to target 10 mg OD (ESC guideline)
Beta-blockers must be introduced at low doses and gradually up-titrated post-MI to avoid haemodynamic compromise. At HR 62, prescribing 10 mg bisoprolol risks symptomatic bradycardia, heart block, and worsening cardiogenic shock if any degree of left ventricular dysfunction is present. The target of 10 mg is achieved over months — not on day 2. Both the ACEi and beta-blocker being started at maximum doses simultaneously compounds this risk substantially.
⚠ Bradycardia and hypotension risk — compounded with ramipril error
E5
Furosemide 500 mg — 10× the standard dose
Wrong dose
▼
As prescribed
Furosemide 500 mg OD PO
Correct
Furosemide 40 mg OD PO — standard starting dose for fluid overload
The standard oral furosemide dose for mild heart failure and fluid overload is 40 mg once daily in the morning. 500 mg doses are occasionally used in end-stage renal failure under specialist supervision. In this patient, 500 mg furosemide would cause catastrophic electrolyte derangement (severe hypokalaemia, hyponatraemia, hypomagnesaemia), acute kidney injury from volume depletion, and dangerous hypotension. In the context of also receiving ramipril 10 mg and bisoprolol 10 mg, this chart compounds three separate haemodynamic hazards simultaneously.
⚠ Severe electrolyte disturbance / acute kidney injury
E6
Metformin not withheld — 24 hours post-contrast angiogram
Contraindicated
▼
As prescribed
Metformin 1g BD continued day after contrast angiogram
Correct
Withhold metformin for 48 hours after iodinated contrast. Recheck U&E at 48h — restart only if eGFR remains ≥45 (MHRA guidance)
Iodinated contrast agents can cause contrast-induced nephropathy (CIN), reducing eGFR transiently. Metformin is renally excreted — if renal function deteriorates, metformin accumulates and inhibits hepatic lactate metabolism, causing metformin-associated lactic acidosis (MALA) with mortality up to 50%. Current MHRA guidance (2022) states metformin should be withheld for 48 hours after contrast, with U&E checked before restarting. This applies regardless of baseline renal function. Remember SADMANS for all acute admissions and procedural contexts.
⚠ Lactic acidosis risk post-contrast